Human immunodeficiency virus type 2 infection in Spain

被引:13
作者
Machuca, A
Soriano, V
Gutiérrez, M
Holguín, A
Aguilera, A
Caballero, E
Cilla, G
机构
[1] Hosp Carlos III, Serv Infect Dis & Microbiol, Inst Salud Carlos III, Madrid, Spain
[2] Hosp Xeral, Microbiol Serv, Santiago, Spain
[3] Hosp Gen Valle Hebron, Microbiol Serv, Barcelona, Spain
[4] Hosp Virgen Aranzazu, Microbiol Serv, San Sebastian, Spain
关键词
HIV-2; epidemiology; diagnosis; subtypes;
D O I
10.1159/000024958
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The fi rst cases of human immunodeficiency virus type 2 (HIV-2) infection in Spain were identified in 1988, in 3 African immigrants living in Barcelona, Since then, up to December 1998, 92 individuals with HIV-2 infection have been reported in Spain. Most are adult men, infected through heterosexual contacts, originating from West African countries, and currently living in the largest urban Spanish cities. Fifteen individuals have developed AIDS, meanwhile the rest remain asymptomatic. For 22 subjects, HIV-2 subtyping was performed on proviral DNA, 16 being infected with subtype A (8 Spanish born and 8 African immigrants) and the remaining with subtype B (two Spanish born and 4 originating from Equatorial Guinea). Coinfection with HIV-1 was demonstrated in 9 individuals. In conclusion, HIV-2 is currently circulating in Spain with a low prevalence and without evidence for increase over time.
引用
收藏
页码:37 / 42
页数:6
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