Synthesis, antimicrobial activity and binding properties of calix[4]arene based vancomycin mimics

被引：119

作者：

Casnati, A

Fabbi, M

Pelizzi, N

Pochini, A

Sansone, F

Ungaro, R

DiModugno, E

Tarzia, G

机构：

[1] DIPARTIMENTO CHIM ORGAN & IND,I-43100 PARMA,ITALY

[2] GLAXO RES LABS,I-37138 VERONA,ITALY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 22期

关键词：

D O I：

10.1016/S0960-894X(96)00493-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D- or L- alanine units and a diethylentriamine segment. Copyright (C) 1996 Elsevier Science Ltd

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页码：2699 / 2704

页数：6

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