Fatal anaphylactic shock during a fluorescein angiography

被引:44
作者
Fineschi, V
Monasterolo, G
Rosi, R
Turillazzi, E
机构
[1] Univ Siena, Dept Forens Sci, Policlin Le Scotte, I-53100 Siena, Italy
[2] Hosp Fossano, Lab Chem Clin & Microbiol Anal, Cuneo, Italy
[3] Le Scotte Hosp, Intens Care Unit, I-53100 Siena, Italy
关键词
retinal fluorescein angiography; fatal anaphylactic shock; mast-cell tryptase;
D O I
10.1016/S0379-0738(98)00205-9
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
The Authors describe an extremely rare fatal case (sixth case in the literature) of anaphylactic shock following a fluorescein angiography. This is the first report in which the diagnosis of anaphylactic reaction to the dye was made through laboratory analyses. The diagnosis of fatal shock due to sodium fluorescein was made based on clinical, laboratory and immunohistochemical data. Mast-cell tryptase was dosed in serum and a pulmonary immunohistochemical evaluation was performed. Tryptase, a neutral protease of human mast-cells is a potentially important indicator of mast-cell involvement in anaphylactic events. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:137 / 142
页数:6
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