Regioselective hypervalent-iodine (III)-mediated dearomatizing phenylation of phenols through direct ligand coupling

被引：105

作者：

Ozanne-Beaudenon, A

Quideau, S

机构：

[1] Inst Europeen Chim & Biol, F-33607 Pessac, France

[2] Univ Bordeaux 1, Chim Organ & Organomet Lab, CNRS, UMR5802,Ctr Rech Chim Mol, F-33405 Talence, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 43期

关键词：

aromaticity; hypervalent compounds; iodine; reaction mechanisms; regioselectivity;

D O I：

10.1002/anie.200501638

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Dearomatization: Treatment of phenols and naphthols substituted at the ortho position by a small electron-donating group D with chlorodiphenyl-λ3-iodane leads to their regioselective ortho phenylation to give cyclohexa-2,4-dienone derivatives (see scheme). The mechanism of this reaction involves a nonradical direct coupling of the ligands. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：7065 / 7069

页数：5

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