The Vibrio harveyi GTPase CgtAV is essential and is associated with the 50S ribosomal subunit

被引：30

作者：

Sikora, AE

Zielke, R

Datta, K

Maddock, JR

机构：

[1] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA

[2] Univ Gdansk, Dept Mol Biol, PL-80822 Gdansk, Poland

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 03期

关键词：

D O I：

10.1128/JB.188.3.1205-1210.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

It was previously reported that unlike the other obg/cgtA GTPases, the Vibrio harveyi cgtA(V) is not essential. Here we show that cgtA, was not disrupted in these studies and is, in fact, essential for viability. Depletion of CgtA(V) did not result in cell elongation. CgtA(V) is associated with the large ribosomal particle. In light of our results, we predict that the V. harveyi CgtA(V) protein plays a similar essential role to that seen for Obg/CgtA proteins in other bacteria.

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页码：1205 / 1210

页数：6

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