Seven Ways to Preserve the Miracle of Antibiotics

被引:275
作者
Bartlett, John G. [1 ]
Gilbert, David N. [2 ]
Spellberg, Brad [3 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA
[2] Providence Portland Med Ctr, Dept Med Educ, Portland, OR USA
[3] Liu Vaccine Ctr, Torrance, CA USA
关键词
antibiotic resistance; antibiotic salvage; European Union; stewardship; molecular diagnostics; DOUBLE-BLIND; ANTIMICROBIALS; SURVEILLANCE; PNEUMONIA;
D O I
10.1093/cid/cit070
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Antibiotic resistance is a well-acknowledged crisis with no clearly defined comprehensive, national corrective plan. We propose a number of interventions that, collectively, could make a large difference. These include collection of data to inform decisions, efforts to reduce antibiotic abuse in people and animals, great emphasis on antibiotic stewardship, performance incentives, optimal use of newer diagnostics, better support for clinical and basic resistance-related research, and novel methods to foster new antibiotic development.
引用
收藏
页码:1445 / 1450
页数:6
相关论文
共 41 条
  • [1] Changes in the use of antimicrobials and the effects on productivity of swine farms in Denmark
    Aarestrup, Frank M.
    Jensen, Vibeke F.
    Emborg, Hanne-Dorthe
    Jacobsen, Erik
    Wegener, Henrik C.
    [J]. AMERICAN JOURNAL OF VETERINARY RESEARCH, 2010, 71 (07) : 726 - 733
  • [2] The Expansion of the Microbiological Spectrum of Brain Abscesses with Use of Multiple 16S Ribosomal DNA Sequencing
    Al Masalma, Mouhamad
    Armougom, Fabrice
    Scheld, W. Michael
    Dufour, Henri
    Roche, Pierre-Hugues
    Drancourt, Michel
    Raoult, Didier
    [J]. CLINICAL INFECTIOUS DISEASES, 2009, 48 (09) : 1169 - 1178
  • [3] [Anonymous], COCHRANE DATABASE SY
  • [4] Development of standardized methods for analysis of changes in antibacterial use in hospitals from 18 European countries: the European Surveillance of Antimicrobial Consumption (ESAC) longitudinal survey, 2000-06
    Ansari, F.
    Molana, H.
    Goossens, H.
    Davey, P.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2010, 65 (12) : 2685 - 2691
  • [5] Arnold HM, 2011, SEMIN RESP CRIT CARE, V12, P2062
  • [6] Diagnostic Tests for Agents of Community-Acquired Pneumonia
    Bartlett, John G.
    [J]. CLINICAL INFECTIOUS DISEASES, 2011, 52 : S296 - S304
  • [7] Dosing of colistin-back to basic PK/PD
    Bergen, Phillip J.
    Li, Jian
    Nation, Roger L.
    [J]. CURRENT OPINION IN PHARMACOLOGY, 2011, 11 (05) : 464 - 469
  • [8] Multiplex PCR and Emerging Technologies for the Detection of Respiratory Pathogens
    Caliendo, Angela M.
    [J]. CLINICAL INFECTIOUS DISEASES, 2011, 52 : S326 - S330
  • [9] Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults - A randomized trial
    Chastre, J
    Wolff, M
    Fagon, JY
    Chevret, S
    Thomas, F
    Wermert, D
    Clementi, E
    Gonzalez, J
    Jusserand, D
    Asfar, P
    Perrin, D
    Fieux, F
    Aubas, S
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (19): : 2588 - 2598
  • [10] Trial networks move beyond single-disease strategies
    Dolgin, Elie
    [J]. NATURE MEDICINE, 2011, 17 (12) : 1525 - 1525