Allogeneic vascularized grafting of a human knee joint with postoperative immunosuppression

被引：29

作者：

Hofmann, GO

Kirschner, MH

Wagner, FD

Land, W

Buhren, V

机构：

[1] UNIV MUNICH,CHIRURG KLIN & POLIKLIN,ABT TRANSPLANTAT CHIRURG,MUNICH,GERMANY

[2] UNIV MUNICH,INST CHIRURG FORSCH,MUNICH,GERMANY

来源：

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY | 1997年 / 116卷 / 03期

关键词：

D O I：

10.1007/s004020050085

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

In this paper we report the first successful allogeneic vascularized transplantation of a fresh and perfused human knee joint. A 17-year-old male had lost his knee in a motorvehicle accident. The graft was harvested from a multiorgan donor, perfused with 41 UW solution and transplanted within 21 h. Osteosyntheses were performed employing intramedullary nails. Immunosuppression was based mainly on two drugs: cyclosporin A and azathioprine. Five months after the operation the patient is fully mobilized, and the graft perfusion still intact. Osteotomies of the femur and tibia demonstrate callus formation and osseous consolidation.

引用

页码：125 / 128

页数：4

共 12 条

[1]

CHIRON P, 1990, INT ORTHOP, V14, P269

[2]

DOI K, 1989, J BONE JOINT SURG BR, V71, P576, DOI 10.1302/0301-620X.71B4.2768300

[3] TRANSPLANTATION OF THE CANINE KNEE-JOINT ON A VASCULAR PEDICLE - A PRELIMINARY-STUDY [J].