Irreversible assembly of membrane fusion machines

被引：4

作者：

Barrick, D ^{[1
]}

Hughson, FM

机构：

[1] Johns Hopkins Univ, Dept Biophys, Baltimore, MD 21218 USA

[2] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2002年 / 9卷 / 02期

关键词：

D O I：

10.1038/nsb0202-78

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A large kinetic barrier prevents spontaneous disassembly of SNARE complexes, complicating thermodynamic measurements and resulting in hysteresis. Nonetheless, this kinetic barrier is probably crucial for SNARE function.

引用

页码：78 / 80

页数：3

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