Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

被引:70
作者
Eckerle, Isabella [1 ]
Corman, Victor M. [1 ]
Mueller, Marcel A. [1 ]
Lenk, Matthias [2 ]
Ulrich, Rainer G. [2 ]
Drosten, Christian [1 ]
机构
[1] Univ Bonn, Med Ctr, D-53105 Bonn, Germany
[2] Friedrich Loeffler Inst, Greifswald, Germany
关键词
RESPIRATORY SYNDROME CORONAVIRUS; BATS; VIRUS;
D O I
10.3201/eid2002.131182
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.
引用
收藏
页码:276 / 279
页数:4
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