Novel estimation of lipophilic behaviour of polychlorinated biphenyls

被引:36
作者
Khadikar, PV [1 ]
Singh, S [1 ]
Shrivastava, A [1 ]
机构
[1] Laxmi Fumigat & Pest Control Pvt Ltd, Div Res, Indore 452007, Madhya Pradesh, India
关键词
D O I
10.1016/S0960-894X(02)00086-0
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A novel method has been developed for the estimation of lipophilic behaviour of polychlorinated biphenyls (PCBs) using the recently introduced Padmakar-Ivan (PI) index. The results obtained are compared with the earlier reported Abraham method. The statistical analyses showed that the proposed method based on the PI index is quite useful. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码:1125 / 1128
页数:4
相关论文
共 20 条
[1]   QSAR prediction of toxicity of nitrobenzenes [J].
Agrawal, VK ;
Khadikar, PV .
BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (11) :3035-3040
[2]   CORRELATIONS BETWEEN CHEMICAL-STRUCTURE AND NORMAL BOILING POINTS OF ACYCLIC ETHERS, PEROXIDES, ACETALS, AND THEIR SULFUR ANALOGS [J].
BALABAN, AT ;
KIER, LB ;
JOSHI, N .
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1992, 32 (03) :237-244
[3]  
Bintein S, 1993, SAR QSAR Environ Res, V1, P29, DOI 10.1080/10629369308028814
[4]  
CHATERJEE S, 2000, REGRESSION ANAL EXAM
[5]  
ERICKSON MD, 1986, ANAL CHEM PCBS
[6]  
HIGUCHI K, 1976, PCB POISONING POLLUT, P147
[7]  
KARMARKAR S, 1997, J SERB CHEM SOC, V62, P227
[8]  
Khadikar PV, 2000, NATL ACAD SCI LETT, V23, P124
[9]   QSAR study on toxicity to aqueous organisms using the PI index [J].
Khadikar, PV ;
Phadnis, A ;
Shrivastava, A .
BIOORGANIC & MEDICINAL CHEMISTRY, 2002, 10 (04) :1181-1188
[10]  
Khadikar PV, 2000, NATL ACAD SCI LETT, V23, P165