Parallel-operated stirred-columns for microbial process development

被引：20

作者：

Weuster-Botz, D ^{[1
]}

Stevens, S

Hawrylenko, A

机构：

[1] Tech Univ Munich, Inst Biochem Engn, D-85748 Garching, Germany

[2] Res Ctr Julich, Inst Biotechnol, D-52425 Julich, Germany

[3] Infors AG, CH-4103 Bottmingen, Switzerland

来源：

BIOCHEMICAL ENGINEERING JOURNAL | 2002年 / 11卷 / 01期

关键词：

bioreactors; oxygen transfer; aeration; power input; stirred-column;

D O I：

10.1016/S1369-703X(02)00010-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Magnetically driven stirred-columns designed for parallel operation in an incubator chamber operated like shaking flasks were characterized with respect to oxygen mass transfer and volume related power input. Power inputs of 770+/-60 W m(-3) were measured at a stirrer speed of 900 rpm, which is in the same order of magnitude as in stirred-tank reactors and shaking flasks. Oxygen mass transfer coefficients of up to 0.34+/-0.05 s(-1) were achieved in stirred-columns (E. coli medium). Due to their similarity to stirred-tank reactors with respect to oxygen mass transfer and power input, parallel-operated stirred-columns may be a useful new tool for microbial process development. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：69 / 72

页数：4

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