Developing and implementing an institute-wide data sharing policy

被引:27
作者
Dyke, Stephanie O. M. [1 ]
Hubbard, Tim J. P. [1 ]
机构
[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
来源
GENOME MEDICINE | 2011年 / 3卷
基金
英国惠康基金;
关键词
GENOME; SCIENCE;
D O I
10.1186/gm276
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The Wellcome Trust Sanger Institute has a strong reputation for prepublication data sharing as a result of its policy of rapid release of genome sequence data and particularly through its contribution to the Human Genome Project. The practicalities of broad data sharing remain largely uncharted, especially to cover the wide range of data types currently produced by genomic studies and to adequately address ethical issues. This paper describes the processes and challenges involved in implementing a data sharing policy on an institute-wide scale. This includes questions of governance, practical aspects of applying principles to diverse experimental contexts, building enabling systems and infrastructure, incentives and collaborative issues.
引用
收藏
页数:8
相关论文
共 46 条
[1]   A map of human genome variation from population-scale sequencing [J].
Altshuler, David ;
Durbin, Richard M. ;
Abecasis, Goncalo R. ;
Bentley, David R. ;
Chakravarti, Aravinda ;
Clark, Andrew G. ;
Collins, Francis S. ;
De la Vega, Francisco M. ;
Donnelly, Peter ;
Egholm, Michael ;
Flicek, Paul ;
Gabriel, Stacey B. ;
Gibbs, Richard A. ;
Knoppers, Bartha M. ;
Lander, Eric S. ;
Lehrach, Hans ;
Mardis, Elaine R. ;
McVean, Gil A. ;
Nickerson, DebbieA. ;
Peltonen, Leena ;
Schafer, Alan J. ;
Sherry, Stephen T. ;
Wang, Jun ;
Wilson, Richard K. ;
Gibbs, Richard A. ;
Deiros, David ;
Metzker, Mike ;
Muzny, Donna ;
Reid, Jeff ;
Wheeler, David ;
Wang, Jun ;
Li, Jingxiang ;
Jian, Min ;
Li, Guoqing ;
Li, Ruiqiang ;
Liang, Huiqing ;
Tian, Geng ;
Wang, Bo ;
Wang, Jian ;
Wang, Wei ;
Yang, Huanming ;
Zhang, Xiuqing ;
Zheng, Huisong ;
Lander, Eric S. ;
Altshuler, David L. ;
Ambrogio, Lauren ;
Bloom, Toby ;
Cibulskis, Kristian ;
Fennell, Tim J. ;
Gabriel, Stacey B. .
NATURE, 2010, 467 (7319) :1061-1073
[2]   Standard cooperating procedures [J].
不详 .
NATURE GENETICS, 2011, 43 (06) :501-501
[3]   Data producers deserve citation credit [J].
不详 .
NATURE GENETICS, 2009, 41 (10) :1045-1045
[4]  
[Anonymous], M ORG WELLC TRUST HE
[5]  
[Anonymous], 2010, MIT Sloan Research Paper no. 4773-10
[6]   An international framework to promote access to data [J].
Arzberger, P ;
Schroeder, P ;
Beaulieu, A ;
Bowker, G ;
Casey, K ;
Laaksonen, L ;
Moorman, D ;
Uhlir, P ;
Wouters, P .
SCIENCE, 2004, 303 (5665) :1777-1778
[7]   Genomic sequence information should be released immediately and freely in the public domain [J].
Bentley, DR .
SCIENCE, 1996, 274 (5287) :533-534
[8]   Science as a public enterprise: the case for open data [J].
Boulton, Geoffrey ;
Rawlins, Michael ;
Vallance, Patrick ;
Walport, Mark .
LANCET, 2011, 377 (9778) :1633-1635
[9]   Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls [J].
Burton, Paul R. ;
Clayton, David G. ;
Cardon, Lon R. ;
Craddock, Nick ;
Deloukas, Panos ;
Duncanson, Audrey ;
Kwiatkowski, Dominic P. ;
McCarthy, Mark I. ;
Ouwehand, Willem H. ;
Samani, Nilesh J. ;
Todd, John A. ;
Donnelly, Peter ;
Barrett, Jeffrey C. ;
Davison, Dan ;
Easton, Doug ;
Evans, David ;
Leung, Hin-Tak ;
Marchini, Jonathan L. ;
Morris, Andrew P. ;
Spencer, Chris C. A. ;
Tobin, Martin D. ;
Attwood, Antony P. ;
Boorman, James P. ;
Cant, Barbara ;
Everson, Ursula ;
Hussey, Judith M. ;
Jolley, Jennifer D. ;
Knight, Alexandra S. ;
Koch, Kerstin ;
Meech, Elizabeth ;
Nutland, Sarah ;
Prowse, Christopher V. ;
Stevens, Helen E. ;
Taylor, Niall C. ;
Walters, Graham R. ;
Walker, Neil M. ;
Watkins, Nicholas A. ;
Winzer, Thilo ;
Jones, Richard W. ;
McArdle, Wendy L. ;
Ring, Susan M. ;
Strachan, David P. ;
Pembrey, Marcus ;
Breen, Gerome ;
St Clair, David ;
Caesar, Sian ;
Gordon-Smith, Katherine ;
Jones, Lisa ;
Fraser, Christine ;
Green, Elain K. .
NATURE, 2007, 447 (7145) :661-678
[10]   The role of a bioresource research impact factor as an incentive to share human bioresources [J].
Cambon-Thomsen, Anne ;
Thorisson, Gudmundur A. ;
Mabile, Laurence .
NATURE GENETICS, 2011, 43 (06) :503-504