Effect of ions and other compatible solutes on enzyme activity, and its implication for biocatalysis using ionic liquids

被引：324

作者：

Zhao, H ^{[1
]}

机构：

[1] Savannah State Univ, Dept Nat Sci & Math, Chem Program, Savannah, GA 31404 USA

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2005年 / 37卷 / 1-6期

基金：

美国国家科学基金会;

关键词：

enzyme; activity; stability; ion; Hofmeister series; ionic liquid;

D O I：

10.1016/j.molcatb.2005.08.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of ions on enzyme activity and stability usually follows the Hofmeister series (or the kosmotropicity order): kosmotropic anions and chaotropic cations stabilize enzymes while chaotropic anions and kosmotropic cations destabilize them. The effect of ionic liquids (ILs) on the enzyme activity/stability/enantioselectivity is complicated especially when there is no or little water presence in the IL media. However, when aqueous solutions of hydrophilic ILs are employed as reaction media, the enzyme seems to follow the Hofmeister series since ILs dissociate into individual ions in water. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：16 / 25

页数：10

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