Treatment of facial rhytids with a nonablative laser: A clinical and histologic study

被引:115
作者
Menaker, GM
Wrone, DA
Williams, RM
Moy, RL
机构
[1] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 USA
[2] Univ Calif Los Angeles, Los Angeles, CA 90024 USA
关键词
D O I
10.1046/j.1524-4725.1999.08158.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BACKGROUND. Current facial resurfacing modalities (laser, chemical peels, and dermabrasion) remove the epidermis and thus cause open wounds which carry significant risks and extended recovery periods. The nonablative laser is a novel Nd: YAG system designed to alleviate facial rhytids without injuring the epidermis. This new modality may offer patients rhytid removal without the risk seen in currently used resurfacing techniques. OBJECTIVE. TO describe a novel nonablative laser system and assess its safety profile and efficacy. METHODS. Ten patients received laser treatments of their periocular rhytids and postauricular skin. Clinical variables (rhytid severity, hyperpigmentation, hypopigmentation, scarring, and level of discomfort) were assessed at 1 and 3 months posttreatment,:Postauricular skin biopsies were taken both pre- and posttreatment for histologic analysis; RESULTS. Patient discomfort was minimal. Three months post- treatment, 4 of 10 patients showed a one-point improvement in periocular rhytid severity when judged on a six-point scale. The results were not statistically significant. Biopsy analysis showed a small posttreatment increase in the amount of dermal collagen in three patients. A small decrease in collagen was noted in one patient. Three patients. also showed a small posttreatment increase in the degree homogenization of dermal collagen. No change from baseline was noted in other assessed histological parameters. Complications observed included hyperpigmentation in three patients and pitted scarring in three patients. CONCLUSIONS. The nonablative laser gave clinically subtle and statistically insignificant improvement-in rhytid severity. Unfortunately its use was associated with complications that included hyperpigmentation and scarring. This technology may eventually offer patients a new resurfacing option, but its efficacy and complication rate must be improved first.
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页码:440 / 444
页数:5
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