Genital tract infections among HIV-infected pregnant women in Malawi, Tanzania and Zambia

被引：35

作者：

Aboud, S. ^{[1
]}

Msamanga, G.

Read, J. S. ^{[2
]}

Mwatha, A.

Chen, Y. Q. ^{[3
]}

Potter, D. ^{[4
]}

Valentine, M. ^{[5
]}

Sharma, U. ^{[6
]}

Hoffmann, I. ^{[7
]}

Taha, T. E. ^{[8
]}

Goldenberg, R. L. ^{[9
]}

Fawzi, W. W. ^{[10
,11
]}

机构：

[1] Muhimbili Univ Hlth & Allied Sci, Dept Microbiol & Immunol, Dar Es Salaam, Tanzania

[2] NICHD, Pediat Adolescent & Maternal AIDS Branch, NIH, DHHS, Bethesda, MD USA

[3] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

[4] Univ Alabama, Sch Publ Hlth, Birmingham, AL 35294 USA

[5] Family Hlth Int, Res Triangle Pk, NC 27709 USA

[6] NIAID, Prevent Sci Program, NIH, Bethesda, MD 20892 USA

[7] Univ N Carolina, Chapel Hill, NC USA

[8] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[9] Drexel Univ, Dept Obstet & Gynaecol, Philadelphia, PA 19104 USA

[10] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA

[11] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2008年 / 19卷 / 12期

关键词：

sexually transmitted infections; genital tract infections; pregnant women; human immunodeficiency virus; Africa;

D O I：

10.1258/ijsa.2008.008067

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The aim of this study was to compare the prevalence and factors associated with genital tract infections among HIV-infected pregnant women from African sites. Participants were recruited from Blantyre and Lilongwe, Malawi; Dar es Salaam, Tanzania; and Lusaka, Zambia. Genital tract infections were assessed at baseline. Of 2627 eligible women enrolled, 2292 were HIV-infected. Of these, 47.8% had bacterial vaginosis (BV), 22.4% had vaginal candidiasis, 18.8% had trichomoniasis, 8.5% had genital warts, 2.6% had chlamydia infection, 2.2% had genital ulcers and 1.7% had gonorrhoea. The main factors associated with genital tract infections included genital warts (adjusted odds ratio [AOR] 1.8, 95% CI 1.2-2.7), genital ulcers (AOR 2.4, 95% CI 1.2-5.1) and abnormal vaginal discharge (AOR 2.5, 95% CI 1.9-3.3) for trichomoniasis. BV was the most common genital tract infection followed by candidiasis and trichomoniasis. Differences in burdens and risk factors call for enhanced interventions for identification of genital tract infections among HIV-infected women.

引用

页码：824 / 832

页数：9

共 21 条

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