Salt handling and hypertension

被引：79

作者：

O'Shaughnessy, KM

Karet, FE

机构：

[1] Univ Cambridge, Clin Pharmacol Unit, Cambridge CB2 1TN, England

[2] Univ Cambridge, Div Renal Med, Cambridge CB2 1TN, England

[3] Univ Cambridge, Dept Med Genet, Cambridge CB2 1TN, England

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2004年 / 113卷 / 08期

关键词：

D O I：

10.1172/JCI200421560

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The kidney plays a central role in our ability to maintain appropriate sodium balance, which is critical to determination of blood pressure. In this review we outline current knowledge of renal salt handling at the molecular level, and, given that Westernized societies consume more salt than is required for normal physiology, we examine evidence that the lowering of salt intake can combat hypertension.

引用

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页码：1075 / 1081

页数：7

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