TRENDS IN NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE AMONG CHILDREN ATTENDING DAYCARE CENTERS IN SOUTHEASTERN FRANCE FROM 1999 TO 2006

被引:27
作者
Dunais, Brigitte [1 ]
Bruno, Pascale [2 ]
Carsenti-Dellamonica, Helene
Touboul, Pia [2 ]
Dellamonica, Pierre
Pradier, Christian [2 ]
机构
[1] CHU Nice, Hop Archet 1, Dept Infect Dis, Serv Infectiol, F-06202 Nice, France
[2] CHU Nice, Dept Sante Publ, F-06202 Nice, France
关键词
pneumococcal nasopharyngeal carriage; children's daycare centers; pneumococcal conjugate vaccine; antibiotic use;
D O I
10.1097/INF.0b013e31817bb8cf
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Pneumococcal nasopharyngeal carriage, serotype distribution, and penicillin-susceptibility were monitored among children attending daycare centers in France from 1999 to 2006 to assess the impact of pneumococcal Conjugate vaccine and antibiotic-reducing policies. Pneumococcal carriage remained stable. Immunization rates reached 68% in 2006. Serotype distribution shifted significantly from vaccine serotypes to vaccine-related and nonvaccine serotypes. Antibiotic treatments fell by 50%.
引用
收藏
页码:1033 / 1035
页数:3
相关论文
共 11 条
[1]   Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children [J].
Bogaert, D ;
van Belkum, A ;
Sluijter, M ;
Luijendijk, A ;
de Groot, R ;
Rümke, HC ;
Verbrugh, HA ;
Hermans, PWM .
LANCET, 2004, 363 (9424) :1871-1872
[2]   Impact of pneumococcal conjugate vaccine and of reduction of antibiotic use on nasopharyngeal carriage of nonsusceptible pneumococci in children with acute otitis media [J].
Cohen, Robert ;
Levy, Corinne ;
de La Rocque, France ;
Gelbert, Nathalie ;
Wollner, Alain ;
Fritzell, Bernard ;
Bonnet, Eric ;
Tetelboum, Robert ;
Varon, Emmanuelle .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2006, 25 (11) :1001-1007
[3]   Epidemiology and antibiotic susceptibility of nasopharyngeal S-pneumoniae and H-influenzae isolated from children attending day-care centers in 3 french departments [J].
Dellamonica, P ;
Pradier, C ;
Leroy, J ;
Carsenti-Etesse, H ;
Dupont, MJ ;
Roussel-Delvallez, M ;
Dabernat, H ;
Dunais, B ;
Martinot, A ;
Estavoyer, JM ;
Grandbastien, B ;
Guillemot, D ;
De Bels, F .
MEDECINE ET MALADIES INFECTIEUSES, 2002, 32 (12) :650-661
[4]   Reduction of antibiotic use in the community reduces the rate of colonization with penicillin G-nonsusceptible Streptococcus pneumoniae [J].
Guillemot, D ;
Varon, E ;
Bernède, C ;
Weber, P ;
Henriet, L ;
Simon, S ;
Laurent, C ;
Lecoeur, H ;
Carbon, C .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (07) :930-938
[5]   Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004 [J].
Huang, SS ;
Platt, R ;
Rifas-Shiman, SL ;
Pelton, SI ;
Goldmann, D ;
Finkelstein, JA .
PEDIATRICS, 2005, 116 (03) :E408-E413
[6]  
HUANG SS, 2006, PEDIATRICS, V117, P593
[7]   Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae [J].
Kyaw, MH ;
Lynfield, R ;
Schaffner, W ;
Craig, AS ;
Hadler, J ;
Reingold, A ;
Thomas, AR ;
Harrison, LH ;
Bennett, NM ;
Farley, MM ;
Facklam, RR ;
Jorgensen, JH ;
Besser, J ;
Zell, ER ;
Schuchat, A ;
Whitney, CG .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (14) :1455-1463
[8]   Acute otitis media due to penicillin-nonsusceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccine [J].
McEllistrem, MC ;
Adams, JM ;
Patel, K ;
Mendelsohn, AB ;
Kaplan, SL ;
Bradley, JS ;
Schutze, GE ;
Kim, KS ;
Mason, EO ;
Wald, ER .
CLINICAL INFECTIOUS DISEASES, 2005, 40 (12) :1738-1744
[9]   Antibacterial use and Streptococcus pneumoniae penicillin resistance:: A temporal relationship model [J].
Mera, Robertino M. ;
Miller, Linda A. ;
White, Anthony .
MICROBIAL DRUG RESISTANCE, 2006, 12 (03) :158-163
[10]   Pneumococcal vaccine - Direct and indirect ("herd") effects [J].
Musher, DM .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (14) :1522-1524