Organized Blood Pressure Control Programs to Prevent Stroke in Australia Would They Be Cost-Effective?

被引:15
作者
Cadilhac, Dominique A. [1 ,2 ,3 ,4 ]
Carter, Rob [4 ]
Thrift, Amanda G. [1 ,5 ,6 ]
Dewey, Helen M. [2 ,3 ,7 ]
机构
[1] Monash Univ, So Clin Sch, Clayton, Vic 3168, Australia
[2] Florey Neurosci Inst, Natl Stroke Res Inst, Heidelberg, Australia
[3] Univ Melbourne, Melbourne, Vic 3010, Australia
[4] Deakin Univ, Burwood, Vic, Australia
[5] Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic 3004, Australia
[6] Monash Univ, Dept Physiol, Melbourne, Vic 3004, Australia
[7] Austin Hlth, Heidelberg, Vic, Australia
基金
英国医学研究理事会;
关键词
economic model; primary prevention; secondary prevention; stroke; CARDIOVASCULAR-DISEASE; GENERAL-PRACTICE; RECURRENT STROKE; RISK; HYPERTENSION; FRAMINGHAM; HEALTH; PREDICTION; REDUCTION; MORTALITY;
D O I
10.1161/STROKEAHA.111.634949
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose-High blood pressure (BP) is the most important modifiable stroke risk factor. Worldwide high BP in many people is uncontrolled or people are unaware of their BP status. We aimed to assess whether a program of organized multidisciplinary care and medication would be cost-effective for improving BP control for the prevention of stroke. Methods-A novel aspect was to simulate the intervention to match recent primary care initiatives (eg, new Medicare reimbursement items) to ensure policy relevance. Current practice and additional costs of each intervention were included using the best available evidence. The differences in the cost per quality-adjusted life year (QALY) gained for the interventions were compared against current practice. Cost-effectiveness was defined as cost per QALY gained was less than Australian dollars (AUD) 50 000 (societal perspective; reference year 2004). The robustness of estimates was assessed with probabilistic multivariable uncertainty analysis. Results-For primary prevention, the median cost per QALY gained was AUD11 068 (95% uncertainty interval AUD5201 to AUD18 696) in those aged 75 years or older and was AUD17 359 (95% uncertainty interval AUD10 516 to AUD26 036) in those aged 55 to 84 years with >= 15% absolute risk of stroke. Primary prevention interventions were not cost-effective if aged younger than 50 years. The median cost per QALY gained for secondary prevention was AUD1811 and AUD4704, depending on which medications were modeled. Conclusions-Organized care for BP control targeted at specific populations offers excellent value over current practice. Organized care for secondary prevention provided the greatest benefits and strongest cost-effectiveness. Translation into clinical practice requires improved use of relevant Medicare policy in Australia. (Stroke. 2012;43:1370-1375.)
引用
收藏
页码:1370 / +
页数:24
相关论文
共 49 条
[1]  
ACE-Obesity Steering Committee, 2006, ASS COST EFF OBS ACE, P36
[2]  
[Anonymous], 1977, JAMA, V237, P2385
[3]  
[Anonymous], 1982, JAMA, V247, P633
[4]  
[Anonymous], 1984, J Community Health, V9, P314
[5]  
[Anonymous], GUID ASS ABS CARD DI
[6]  
Australian Bureau of Statistics, 2005, AUSTR POP PROJ SER B
[7]  
Australian Government Department of Health and Ageing, 2011, MED BEN SCHED MBS IT
[8]  
Australian Government Department of Health and Ageing, 2004, SCHED PHARM BEN APPR
[9]  
Australian Government Department of Health and Ageing, 2004, MED BEN SCHED BOOK
[10]  
Australian Government Department of Health and Ageing, 2006, ATT D BETT HLTH ALL, P3