Adenoviral vectors for gene transfer

被引：168

作者：

Kovesdi, I

Brough, DE

Bruder, JT

Wickham, TJ

机构：

[1] GenVec Inc., Rockville, MD 20852

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1997年 / 8卷 / 05期

关键词：

D O I：

10.1016/S0958-1669(97)80033-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Adenoviruses began to be developed into highly effective gene expression vectors in the early 1980s. Recently, the increased interest in utilizing this transfer system in vivo has posed new problems for heterologous gene-transfer, spurring a renewed effort in the field of vector development toward solving the structural, immunological and targeting problems posed by gene therapy applications.

引用

页码：583 / 589

页数：7

共 81 条

[1] ALBELDA SM, 1990, CANCER RES, V50, P6757
[2] Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins: Implications for gene therapy
Amalfitano, A
Chamberiain, JS
[J]. GENE THERAPY, 1997, 4 (03) : 258 - 263
[3] Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors
Amalfitano, A
Begy, CR
Chamberlain, JS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (08) : 3352 - 3356
[4] [Anonymous], 1990, VIROLOGY
[5] Effect of the E4 region on the persistence of transgene expression from adenovirus vectors
Armentano, D
Zabner, J
Sacks, C
Sookdeo, CC
Smith, MP
StGeorge, JA
Wadsworth, SC
Smith, AE
Gregory, RJ
[J]. JOURNAL OF VIROLOGY, 1997, 71 (03) : 2408 - 2416
[6] ADENOVIRUS PROTEINS FROM BOTH E1B READING FRAMES ARE REQUIRED FOR TRANSFORMATION OF RODENT CELLS BY VIRAL-INFECTION AND DNA TRANSFECTION
BARKER, DD
BERK, AJ
[J]. VIROLOGY, 1987, 156 (01) : 107 - 121
[7] Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5
Bergelson, JM
Cunningham, JA
Droguett, G
KurtJones, EA
Krithivas, A
Hong, JS
Horwitz, MS
Crowell, RL
Finberg, RW
[J]. SCIENCE, 1997, 275 (5304) : 1320 - 1323
[8] An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
Bischoff, JR
Kim, DH
Williams, A
Heise, C
Horn, S
Muna, M
Ng, L
Nye, JA
SampsonJohannes, A
Fattaey, A
McCormick, F
[J]. SCIENCE, 1996, 274 (5286) : 373 - 376
[9] INTEGRIN ALPHA(V)BETA(3) ANTAGONISTS PROMOTE TUMOR-REGRESSION BY INDUCING APOPTOSIS OF ANGIOGENIC BLOOD-VESSELS
BROOKS, PC
MONTGOMERY, AMP
ROSENFELD, M
REISFELD, RA
HU, TH
KLIER, G
CHERESH, DA
[J]. CELL, 1994, 79 (07) : 1157 - 1164
[10] A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4
Brough, DE
Lizonova, A
Hsu, C
Kulesa, VA
Kovesdi, I
[J]. JOURNAL OF VIROLOGY, 1996, 70 (09) : 6497 - 6501

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