Flexural psoriasis induced by infliximab and adalimumab in a patient with Crohn's disease

被引：23

作者：

Avila Alvarez, A. ^{[1
]}

Garcia-Alonso, L. ^{[1
]}

Solar Boga, A. ^{[1
]}

Garcia-Silva, J. ^{[2
]}

机构：

[1] Complejo Hosp Univ A Coruna, Unidad Gastroenterol Pediat, Serv Pediat, La Coruna, Spain

[2] Complejo Hosp Univ A Coruna, Serv Dermatol, La Coruna, Spain

来源：

ANALES DE PEDIATRIA | 2009年 / 70卷 / 03期

关键词：

Infliximab; Adalimumab; Flexural psoriasis; Inflammatory bowel disease; TNF-ALPHA INHIBITORS; ADVERSE-REACTION; ANTIBODY; THERAPY; ARTHRITIS; LESIONS; ONSET;

D O I：

10.1016/j.anpedi.2008.11.013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Anti-TNF drugs are used increasingly in several diseases with immune-mediated inflammation, not only in rheumatotogical conditions, but also in inflammatory bowel disease and psoriasis. Different side effects have been described over the last few years, including the development of psoriasis or psoriasiform exanthemas. These drugs began to be used in paediatrics during the 90's, therefore paediatricians need to be aware of the adverse effects that may occur. We describe here a flexural psoriasis induced by both infliximab and adalimumab in a paediatric patient with Crohn's Disease. To the best of our knowledge, this is the first reported paediatric case of psoriasis triggered by an anti-TNF drug, as well as the first case of psoriasis induced by adalimumab in patients with inflammatory bowel disease. (C) 2008 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L. All rights reserved.

引用

页码：278 / 281

页数：4

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