New treatments for rheumatoid arthritis - Available and upcoming slow-acting antirheumatic drugs

被引:11
作者
Fye, KH [1 ]
机构
[1] Univ Calif San Francisco, Div Rheumatol, Sch Med, San Francisco, CA 94143 USA
关键词
D O I
10.3810/pgm.1999.10.1.703
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
No single therapeutic agent has been found to be universally effective for rheumatoid arthritis, so regimens using combinations of drugs have become the rule. Recently, several new agents with unique mechanisms of action have been introduced and found to produce Various degrees of clinical benefit. Among these agents are folate and purine antagonists, alkylating agents, and antipyrimidines. Chimeric (mouse/human) monoclonal antibody to tumor necrosis factor-alpha and human recombinant interleukin-l receptor antagonist a ct ait approval for general use but have undergone considerable study.
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页码:82 / +
页数:8
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