A pathogenetic link between non-alcoholic fatty liver disease and celiac disease

被引：29

作者：

Abenavoli, Ludovico ^{[1
]}

Milic, Natasa ^{[2
]}

De Lorenzo, Antonino ^{[3
]}

Luzza, Francesco ^{[1
]}

机构：

[1] Univ Magna Gracia, Dept Hlth Sci, I-88100 Catanzaro, Italy

[2] Univ Novi Sad, Dept Pharm, Novi Sad 21000, Serbia

[3] Univ Roma Tor Vergata, Div Human Nutr, Dept Neurosci, I-00133 Rome, Italy

来源：

ENDOCRINE | 2013年 / 43卷 / 01期

关键词：

Non-alcoholic fatty liver disease; Celiac disease; Intestinal permeability; Microbiota; INCREASED INTESTINAL PERMEABILITY; CONFOUNDING FACTOR; MEDICAL PROGRESS; STEATOHEPATITIS; ENDOTOXEMIA; PREVALENCE; DIAGNOSIS; INJURY;

D O I：

10.1007/s12020-012-9731-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Non-alcoholic fatty liver disease (NAFLD) has recently been recognized as the leading cause of the abnormalities in the liver function tests in the Western countries. Celiac disease (CD) is a permanent immunological intolerance to gluten proteins in genetically predisposed individuals. CD has been reported in 4-13 % of the cases with steatohepatitis, although the pathogenesis of the liver steatosis in CD patients is unclear. Based on the literature data, it can be concluded that the inclusion of serological markers of CD should be a part of the general workup in the patients with steatosis when other causes of the liver disease are excluded and in the patients with NAFLD when metabolic risk factors are not evident.

引用

页码：65 / 67

页数：3

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