Infectious complications of immunosuppressive therapy in patients with rheumatic diseases

被引:86
作者
Segal, BH
Sneller, MC
机构
[1] NIAID,IMMUNOREGULAT LAB,NIH,BETHESDA,MD 20892
[2] NIAID,HOST DEF LAB,NIH,BETHESDA,MD 20892
关键词
D O I
10.1016/S0889-857X(05)70327-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Infection continues to be a major cause of morbidity and mortality in patients with rheumatic diseases. The recognition and treatment of infections in these patients is a particularly difficult task because the spectrum of potential pathogens is broad and the clinical manifestations of infection often mimic those of the underlying rheumatic disease. This article presents a general overview of the immunosuppressive properties of agents commonly used in the treatment of rheumatic diseases and focuses on specific pathogens associated with different immunosuppressive regimens. Also provided is a framework for the diagnostic evaluation and treatment of various infectious syndromes in patients with rheumatic diseases.
引用
收藏
页码:219 / &
页数:20
相关论文
共 93 条
[1]  
ABDOU NI, 1973, CLIN EXP IMMUNOL, V13, P55
[2]  
ABOGUDDAH A, 1991, J RHEUMATOL, V18, P1403
[3]   ALTERNATE-DAY STEROID THERAPY IN LUPUS NEPHRITIS [J].
ACKERMAN, GL .
ANNALS OF INTERNAL MEDICINE, 1970, 72 (04) :511-+
[4]  
ALEPA FP, 1970, ARTHRITIS RHEUM-US, V13, P754
[5]   PULMONARY INVOLVEMENT IN RHEUMATOID-ARTHRITIS [J].
ANAYA, JM ;
DIETHELM, L ;
ORTIZ, LA ;
GUTIERREZ, M ;
CITERA, G ;
WELSH, RA ;
ESPINOZA, LR .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 1995, 24 (04) :242-254
[6]   WEEKLY PULSE METHOTREXATE IN RHEUMATOID-ARTHRITIS - CLINICAL AND IMMUNOLOGICAL EFFECTS IN A RANDOMIZED, DOUBLE-BLIND-STUDY [J].
ANDERSEN, PA ;
WEST, SG ;
ODELL, JR ;
VIA, CS ;
CLAYPOOL, RG ;
KOTZIN, BL .
ANNALS OF INTERNAL MEDICINE, 1985, 103 (04) :489-496
[7]   COMPLEMENT-INDEPENDENT CLEARANCE OF IGG-SENSITIZED ERYTHROCYTES - INHIBITION BY CORTISONE [J].
ATKINSON, JP ;
FRANK, MM .
BLOOD, 1974, 44 (05) :629-637
[8]   THERAPY OF LUPUS NEPHRITIS - CONTROLLED TRIAL OF PREDNISONE AND CYTOTOXIC DRUGS [J].
AUSTIN, HA ;
KLIPPEL, JH ;
BALOW, JE ;
LERICHE, NGH ;
STEINBERG, AD ;
PLOTZ, PH ;
DECKER, JL .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (10) :614-619
[9]   Methotrexate-associated lymphoma in patients with rheumatoid arthritis - Report of two cases [J].
Bachman, TR ;
Sawitzke, AD ;
Perkins, SL ;
Ward, JH ;
Cannon, GW .
ARTHRITIS AND RHEUMATISM, 1996, 39 (02) :325-329
[10]   TREATMENT OF TUBERCULOSIS AND TUBERCULOSIS INFECTION IN ADULTS AND CHILDREN [J].
BASS, JB ;
FARER, LS ;
HOPEWELL, PC ;
OBRIEN, R ;
JACOBS, RF ;
RUBEN, F ;
SNIDER, DE ;
THORNTON, G .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1994, 149 (05) :1359-1374