Epidermal remodelling in psoriasis

被引：34

作者：

Iizuka, H

IshidaYamamoto, A

Honda, H

机构：

[1] JRDC, ERATO, KANEBO INST CANC RES, SAPPORO, HOKKAIDO, JAPAN

[2] JRDC, ERATO, YOSHIZATO MORPHOMATRIX PROJECT, SAPPORO, HOKKAIDO, JAPAN

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1996年 / 135卷 / 03期

关键词：

D O I：

10.1046/j.1365-2133.1996.d01-1003.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Psoriatic hyperproliferative epidermis is characterized by a regular elongation of rete ridges, accompanied by altered keratinization. Another notable finding is close positioning of the vasculature to the suprapapillary epidermis, These architectural/morphological changes are naturally described by a concept of epidermal remodelling based on decreased epidermal turnover time. The recently described positioning of stem cells to the tips of dermal papillae fits nicely with this concept.

引用

页码：433 / 438

页数：6

共 25 条

[1] FLOW CYTOMETRIC IDENTIFICATION OF PROLIFERATIVE SUBPOPULATIONS WITHIN NORMAL HUMAN EPIDERMIS AND THE LOCALIZATION OF THE PRIMARY HYPERPROLIFERATIVE POPULATION IN PSORIASIS [J].