Dynamic mitochondria

被引:93
作者
Yaffe, MP [1 ]
机构
[1] Univ Calif San Diego, Dept Biol, La Jolla, CA 92093 USA
关键词
D O I
10.1038/14101
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mitochondria are commonly found as extended reticular webs whose overall morphology depends on frequent fission and fusion of mitochondrial tubules. These processes require distinct GTP-binding proteins that act at the mitochondrial surface and have central roles In the determination of mitochondrial structure.
引用
收藏
页码:E149 / E150
页数:2
相关论文
共 17 条
[1]   DYNAMICS OF MITOCHONDRIA IN LIVING CELLS - SHAPE CHANGES, DISLOCATIONS, FUSION, AND FISSION OF MITOCHONDRIA [J].
BEREITERHAHN, J ;
VOTH, M .
MICROSCOPY RESEARCH AND TECHNIQUE, 1994, 27 (03) :198-219
[2]   Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast [J].
Berger, KH ;
Sogo, LF ;
Yaffe, MP .
JOURNAL OF CELL BIOLOGY, 1997, 136 (03) :545-553
[3]   The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast [J].
Bleazard, W ;
McCaffery, JM ;
King, EJ ;
Bale, S ;
Mozdy, A ;
Tieu, Q ;
Nunnari, J ;
Shaw, JM .
NATURE CELL BIOLOGY, 1999, 1 (05) :298-304
[4]   MMM1 ENCODES A MITOCHONDRIAL OUTER-MEMBRANE PROTEIN ESSENTIAL FOR ESTABLISHING AND MAINTAINING THE STRUCTURE OF YEAST MITOCHONDRIA [J].
BURGESS, SM ;
DELANNOY, M ;
JENSEN, RE .
JOURNAL OF CELL BIOLOGY, 1994, 126 (06) :1375-1391
[5]   Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase [J].
Hales, KG ;
Fuller, MT .
CELL, 1997, 90 (01) :121-129
[6]   Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p [J].
Hermann, GJ ;
Thatcher, JW ;
Mills, JP ;
Hales, KG ;
Fuller, MT ;
Nunnari, J ;
Shaw, JM .
JOURNAL OF CELL BIOLOGY, 1998, 143 (02) :359-373
[7]   TEMPERATURE-SENSITIVE YEAST MUTANTS DEFECTIVE IN MITOCHONDRIAL INHERITANCE [J].
MCCONNELL, SJ ;
STEWART, LC ;
TALIN, A ;
YAFFE, MP .
JOURNAL OF CELL BIOLOGY, 1990, 111 (03) :967-976
[8]   INTERMEDIATE FILAMENT FORMATION BY A YEAST PROTEIN ESSENTIAL FOR ORGANELLE INHERITANCE [J].
MCCONNELL, SJ ;
YAFFE, MP .
SCIENCE, 1993, 260 (5108) :687-689
[9]   The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast [J].
Otsuga, D ;
Keegan, BR ;
Brisch, E ;
Thatcher, JW ;
Hermann, GJ ;
Bleazard, W ;
Shaw, JM .
JOURNAL OF CELL BIOLOGY, 1998, 143 (02) :333-349
[10]   Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae [J].
Rapaport, D ;
Brunner, M ;
Neupert, W ;
Westermann, B .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (32) :20150-20155