Strategies for the formation of tetrahydropyran rings in the synthesis of natural products

被引：326

作者：

Clarke, Paul A. ^{[1
]}

Santos, Soraia ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 2006卷 / 09期

关键词：

tetrahydropyran; total synthesis; natural products;

D O I：

10.1002/ejoc.200500964

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This microreview surveys the literature over the last five years with regard to construction of functionalised tetrahydropyran (THP) rings in the context of the synthesis of natural products. The overview given is intended to provide a working knowledge of the area for those who are unfamiliar, and to refresh and remind those who do work in the area of the exciting developments in the field. While the construction of the THP rings in a number of natural products has been reviewed, we have attempted to highlight the different strategies by focusing on two natural products, namely phorboxazole and centrolobine as case studies. Over the last five years, these natural products have become a test bed for new methods for the construction of THP rings.

引用

页码：2045 / 2053

页数：9

共 62 条

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