A novel synthetic route to morpholin-2,3-diones from 2-aminoalcohols.

被引：5

作者：

Harwood, LM

Tucker, TT

Angell, R

Finch, H

机构：

[1] UNIV OXFORD,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

[2] GLAXOWELLCOME MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 24期

关键词：

D O I：

10.1016/0040-4039(96)00800-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of dimethyl acetylenedicarboxylate with 2-aminoalcohols possessing a primary amino group gives 3-methoxycarbonylmethylidinemorpholin-2-ones 5. Subsequent ozonolysis furnishes morpholin-2,3-diones 1 in excellent yields. (C) 1996 Elsevier Science Ltd

引用

页码：4217 / 4220

页数：4

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