Role of cytokines and cytokine-producing cells in reperfusion injury to the liver

被引：87

作者：

Lichtman, SN

Lemasters, JJ

机构：

[1] Univ N Carolina, Dept Pediat, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Anat & Cell Biol, Chapel Hill, NC 27599 USA

来源：

SEMINARS IN LIVER DISEASE | 1999年 / 19卷 / 02期

关键词：

reperfusion injury; ischemia; hypoxia;

D O I：

10.1055/s-2007-1007108

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We have categorized reperfusion injury into (I) warm ischemia/reperfusion injury and (2) cold storage/reperfusion injury. Warm ischemia/reperfusion injury is relevant to shock and hepatic surgery, whereas cold storage/reperfusion injury occurs when the liver is procured and transported for transplantation. Different stages of reperfusion injury; cells that mediate each stage; and cytokines involved are described. Understanding the specific cells and cytokines involved in causing reperfusion injury and their timing will encourage the development of therapeutic strategies aimed at preventing and diminishing the consequences of reperfusion injury.

引用

收藏

页码：171 / 187

页数：17

相关论文

共 241 条

[1] Enhanced liver calpain protease activity is a risk factor for dysfunction of human liver allografts [J].

Aguilar, HI ;

Steers, JL ;

Wiesner, RH ;

Krom, RAF ;

Gores, GJ .

TRANSPLANTATION, 1997, 63 (04) :612-614

[2] Selective bowel decontamination of recipients for prevention against liver injury following orthotopic liver transplantation: Evaluation with rat models [J].

Arai, M ;

Mochida, S ;

Ohno, A ;

Arai, S ;

Fujiwara, K .

HEPATOLOGY, 1998, 27 (01) :123-127

[3]

ARAI M, UNPUB TRANSPLANTATIO

[4] PATHOGENIC ROLE OF KUPFFER CELL ACTIVATION IN THE REPERFUSION INJURY OF COLD-PRESERVED LIVER [J].

ARII, S ;

MONDEN, K ;

ADACHI, Y ;

ZHANG, WH ;

HIGASHITSUJI, H ;

FURUTANI, M ;

MISE, M ;

FUJITA, S ;

NAKAMURA, T ;

IMAMURA, M .

TRANSPLANTATION, 1994, 58 (10) :1072-1077

[5] LIVER-TRANSPLANTATION AND HEPATIC SINUSOIDAL CELLS [J].

ARII, S ;

IMAMURA, M .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 1995, 10 :S92-S96

[6] A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia [J].

Arora, AS ;

DeGroen, P ;

Emori, Y ;

Gores, GJ .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1996, 270 (02) :G238-G245

[7] INFLUENCE OF OXYGEN-DERIVED FREE-RADICAL SCAVENGERS ON ISCHEMIC LIVERS [J].

ATALLA, SL ;

TOLEDOPEREYRA, LH ;

MACKENZIE, GH ;

CEDERNA, JP .

TRANSPLANTATION, 1985, 40 (06) :584-590

[8] THE EFFECTS OF DONOR AND RECIPIENT ENDOTOXEMIA ON TNF-ALPHA PRODUCTION AND MORTALITY IN THE RAT MODEL OF SYNGENIC ORTHOTOPIC LIVER-TRANSPLANTATION [J].

AZOULAY, D ;

ASTARCIOGLU, I ;

LEMOINE, A ;

DENNISON, A ;

MATHIEU, D ;

SAULNIER, C ;

CHATENOUD, L ;

REYNES, M ;

BISMUTH, H .

TRANSPLANTATION, 1995, 59 (06) :825-829

[9]

BACHMANN S, 1995, TRANSPLANT P, V27, P741

[10]

BACHMANN S, 1992, TRANSPLANT INT, V5, P108, DOI 10.1111/j.1432-2277.1992.tb01764.x

← 1 2 3 4 5 6 7 8 9 10 →