Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery

被引：24

作者：

Huet, G ^{[1
]}

Castaing, JP ^{[1
]}

Fournier, D ^{[1
]}

Daffé, M ^{[1
]}

Saves, I ^{[1
]}

机构：

[1] Univ Toulouse 3, CNRS, UMR5089, Dept Mol Mech Mycobacterial Infect,Inst Pharmacol, F-31077 Toulouse, France

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 09期

关键词：

D O I：

10.1128/JB.188.9.3412-3414.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The SufBCD complex is an essential component of the SUF machinery of [Fe-S] cluster biogenesis in many organisms. We show here that in Mycobacterium tuberculosis the formation of this complex is dependent on the protein splicing of SufB, suggesting that this process is a potential new target for antituberculous drugs.

引用

页码：3412 / 3414

页数：3

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