Studies on the mechanism of activation of C(7) ethylenediamine substituted mitomycins. Relevance to the proposed mode of action of BMY-25067 and KW-2149

被引:16
作者
Kohn, H
Wang, S
机构
[1] Department of Chemistry, University of Houston, Houston
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0040-4039(96)00279-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Select C(7) ethylenediamine-substituted mitomycins were prepared, and their reactivity toward nonreductive, nucleophilic aziridine ring opening transformations assessed. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:2337 / 2340
页数:4
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