Primary central nervous system lymphoma masquerading as herpes encephalitis: Clinical, magnetic resonance imaging, and pathologic findings

被引:10
作者
Giglio, P
Bakshi, R
Block, S
Ostrow, P
Pullicino, PM
机构
[1] SUNY Buffalo, Buffalo Neuroimaging Anal Ctr, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
[2] SUNY Buffalo, Dept Neurol, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
[3] SUNY Buffalo, Dept Imaging Serv, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
[4] SUNY Buffalo, Dept Pathol Neuropathol, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
[5] SUNY Buffalo, Jacobs Neurol Inst, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
[6] SUNY Buffalo, Kaleida Hlth, Sch Med & Biomed Sci, Buffalo, NY 14203 USA
关键词
magnetic resonance imaging; brain; lymphoma; herpes encephalitis;
D O I
10.1097/00000441-200201000-00011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
An 84-year-old man presented with acute confusion, global aphasia, and fever. Magnetic resonance imaging (MRI) showed hyperintense lesions on T2-weighted and fluid-attenuated inversion recovery (FLAIR) images predominantly affecting the cortical gray matter of the left mesial temporal and inferior frontal lobes, and insula. Acyclovir was prescribed for presumed viral encephalitis. Clinical and MRI worsening prompted a left temporal lobe biopsy that revealed primary central nervous system lymphoma (PCNSL). This case adds to the MRI spectrum of PCNSL and illustrates that it may mimic the clinical and MRI presentation of herpes simplex encephalitis.
引用
收藏
页码:59 / 61
页数:3
相关论文
共 7 条
[1]   Lymphomatosis cerebri presenting as a rapidly progressive dementia: Clinical, neuroimaging and pathologic findings [J].
Bakshi, R ;
Mazziotta, JC ;
Mischel, PS ;
Jahan, R ;
Seligson, DB ;
Vinters, HV .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 1999, 10 (02) :152-157
[2]  
BAKSHI R, 1998, BAKERS CLIN NEUROLOG, P1
[3]   PRIMARY CENTRAL NERVOUS-SYSTEM LYMPHOMA [J].
HOCHBERG, FH ;
MILLER, DC .
JOURNAL OF NEUROSURGERY, 1988, 68 (06) :835-853
[4]  
Johnson BA, 1997, AM J NEURORADIOL, V18, P563
[5]  
ROMANGOLDSTEIN SM, 1992, AM J NEURORADIOL, V13, P1207
[6]  
SCHWAIGHOFER BW, 1989, AM J NEURORADIOL, V10, P725
[7]   Primary central nervous system lymphoma in AIDS: a wider spectrum of CT and MRI findings [J].
Thurnher, MM ;
Rieger, A ;
Kleibl-Popov, C ;
Settinek, U ;
Henk, C ;
Haberler, C ;
Schindler, E .
NEURORADIOLOGY, 2001, 43 (01) :29-35