An expedient protocol of the Biginelli dihydropyrimidine synthesis using carbonyl equivalents

被引：95

作者：

Singh, K

Singh, J

Deb, PK

Singh, H ^{[1
]}

机构：

[1] Guru Nanak Dev Univ, Dept Appl Chem Sci & Technol, Amritsar 143005, Punjab, India

[2] Guru Nanak Dev Univ, Dept Chem, Amritsar 143005, Punjab, India

来源：

TETRAHEDRON | 1999年 / 55卷 / 44期

关键词：

D O I：

10.1016/S0040-4020(99)00760-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one - pot condensation of perhydro-1,3 heterocycles - aldehyde equivalents with ethyl acetoacetate and ureas provides a convenient synthesis of the title compounds with a variety of substituents at C-4. Yields are equivalent or significantly higher than the conventional methods. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：12873 / 12880

页数：8

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