Composition of the essential oil of two Nepeta species and in vitro evaluation of their activity against Helicobacter pylori

被引:52
作者
Kalpoutzakis, E
Aligiannis, N
Mentis, A
Mitaku, S [1 ]
Charvala, C
机构
[1] Univ Athens, Sch Pharm, Div Pharmacognosy, GR-15771 Athens, Greece
[2] Hellenic Pasteur Inst, Bacteriol Lab, Athens, Greece
关键词
D O I
10.1055/s-2001-18851
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The chemical composition of the essential oils obtained from the aerial parts of Nepeta camphorata and Nepeta argolica ssp. dirphya were analysed by GC-MS. A total of 52 components were identified and significant differences (qualitative and quantitative) were observed between the two samples. 1,8-Cineol and two nepetalactones were found to be the major components of the oil of N. camphorata and N. argolica ssp. dirphya respectively. The in vitro activity, of the two oils and the three above mentioned isolated compounds, against 25 clinically isolated and commercial strains of Helicobacter pylori was investigated and some activity was found.
引用
收藏
页码:880 / 883
页数:4
相关论文
共 24 条
[1]  
Adams R.P., 2004, Identification of Essential Oil Components by Gas Chromatography/Quadrupole Mass Spectroscopy
[2]  
Baser K. H. C., 1998, Journal of Essential Oil Research, V10, P179
[3]  
Baser K. H. C., 1998, Journal of Essential Oil Research, V10, P299
[4]   (7R)-TRANS,TRANS-NEPETALACTONE FROM NEPETA-ELLIPTICA [J].
BOTTINI, AT ;
DEV, V ;
GARFAGNOLI, DJ ;
LOHANI, H ;
MATHELA, CS ;
PANT, AK .
PHYTOCHEMISTRY, 1987, 26 (04) :1200-1202
[5]  
Bourrel C., 1993, Journal of Essential Oil Research, V5, P159
[6]   Inhibitory effect of rose oil products on Helicobacter pylori growth in vitro:: preliminary report [J].
Boyanova, L ;
Neshev, G .
JOURNAL OF MEDICAL MICROBIOLOGY, 1999, 48 (07) :705-706
[7]  
Chalchat J. C., 1998, Journal of Essential Oil Research, V10, P423
[8]   THE ESSENTIAL OIL OF NEPETA-NUDA - IDENTIFICATION OF A NEW NEPETALACTONE DIASTEREOISOMER [J].
DEPOOTER, HL ;
NICOLAI, B ;
DEBUYCK, LF ;
GOETGHEBEUR, P ;
SCHAMP, NM .
PHYTOCHEMISTRY, 1987, 26 (08) :2311-2314
[9]   ESSENTIAL ROLE OF UREASE IN PATHOGENESIS OF GASTRITIS INDUCED BY HELICOBACTER-PYLORI IN GNOTOBIOTIC PIGLETS [J].
EATON, KA ;
BROOKS, CL ;
MORGAN, DR ;
KRAKOWKA, S .
INFECTION AND IMMUNITY, 1991, 59 (07) :2470-2475
[10]   STRUCTURE AND STEREOCHEMISTRY OF 4A-BETA,7-ALPHA,7A-BETA-NEPETALACTONE FROM NEPETA-MUSSINI AND ITS RELATIONSHIP TO THE 4A-ALPHA,7-ALPHA,7A-ALPHA AND 4A-ALPHA,7-ALPHA,7A-BETA-NEPETALACTONES FROM N CATARIA [J].
EISENBRAUN, EJ ;
BROWNE, CE ;
IRVINWILLIS, RL ;
MCGURK, DJ ;
ELIEL, EL ;
HARRIS, DL .
JOURNAL OF ORGANIC CHEMISTRY, 1980, 45 (19) :3811-3814