Comparison of the avidity index method and the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion, two methods using a single serum sample for identification of recent HIV infections

被引:31
作者
Martró, E
Suligoi, B
González, V
Bossi, V
Esteve, A
Mei, J
Ausina, V [1 ]
机构
[1] Hosp Univ Germans Trias & Pujol, Ctr Epidemiol Studies HIV AIDS Catalonia, CEESCAT, Microbiol Serv, Badalona 08916, Spain
[2] Univ Autonoma Barcelona, Hosp Germans Trias & Pujol, Dept Genet & Microbiol, Microbiol Serv, Badalona, Spain
[3] Ist Super Sanita, Dept Infect Dis, I-00161 Rome, Italy
[4] Osp Amedeo Savoia, Virol Lab, Turin, Italy
[5] Ctr Dis Control & Prevent, Newborn Screening Qual Assurance Program, Atlanta, GA USA
关键词
D O I
10.1128/JCM.43.12.6197-6199.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A study was designed to compare an avidity index method to the serologic testing algorithm for recent human immunodeficiency virus (HIV) seroconversion (STARHS) for the detection of recent HIV infection. One hundred sixty HIV-positive sera were tested. Both techniques performed similarly in identifying recent infections, although STARHS tended to misclassify more individuals that had long-standing infection as being recently infected.
引用
收藏
页码:6197 / 6199
页数:3
相关论文
共 22 条
[1]  
*CEESCAT, 2005, SIVES 2004 INT HIV S
[2]  
Eggers M, 2000, J MED VIROL, V60, P324, DOI 10.1002/(SICI)1096-9071(200003)60:3&lt
[3]  
324::AID-JMV11&gt
[4]  
3.0.CO
[5]  
2-D
[6]  
Gouws E, 2002, J ACQ IMMUN DEF SYND, V29, P531, DOI 10.1097/00126334-200204150-00015
[7]   New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes [J].
Janssen, RS ;
Satten, GA ;
Stramer, SL ;
Rawal, BD ;
O'Brien, TR ;
Weiblen, BJ ;
Hecht, FM ;
Jack, N ;
Cleghorn, FR ;
Kahn, JO ;
Chesney, MA ;
Busch, MP .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (01) :42-48
[8]   Improved diagnosis of primary Toxoplasma gondii infection in early pregnancy by determination of antitoxoplasma immunoglobulin G avidity [J].
Jenum, PA ;
StrayPedersen, B ;
Gundersen, AG .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (08) :1972-1977
[9]   Performance characteristics of a new less sensitive HIV-1 enzyme immunoassay for use in estimating HIV seroincidence [J].
Kothe, D ;
Byers, RH ;
Caudill, SP ;
Satten, GA ;
Janssen, RS ;
Hannon, WH ;
Mei, JV .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2003, 33 (05) :625-634
[10]   Use of the sensitive/less-sensitive (detuned) EIA strategy for targeting genetic analysis of HIV-1 to recently infected blood donors [J].
Machado, DM ;
Delwart, EL ;
Diaz, RS ;
de Oliveira, CF ;
Alves, K ;
Rawal, BD ;
Sullivan, M ;
Gwinn, M ;
Clark, KA ;
Busch, MP .
AIDS, 2002, 16 (01) :113-119