Respiratory infections and asthma

被引：46

作者：

Pelaia, G

Vatrella, A

Gallelli, L

Renda, T

Cazzola, M ^{[1
]}

Maselli, R

Marsico, SA

机构：

[1] Magna Graecia Univ Catanzaro, Dept Expt & Clin Med, Catanzaro, Italy

[2] Univ Naples 2, Dept Cardiothorac & Resp Sci, Naples, Italy

[3] A Cardarelli Hosp, Dept Resp Med, Unit Pneumol & Allergol, I-80121 Naples, Italy

来源：

RESPIRATORY MEDICINE | 2006年 / 100卷 / 05期

关键词：

asthma; respiratory viruses; atypical bacteria;

D O I：

10.1016/j.rmed.2005.08.025

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Respiratory tract infections caused by both viruses and/or atypical bacteria are involved in the pathogenesis of asthma. In particular, several viruses such as respiratory syncytial virus, rhinovirus and influenza/parainfluenza viruses may favour the expression of the asthmatic phenotype, being also implicated in the induction of disease exacerbations. Within this pathological context, a significant role can also be played by airway bacterial. colonizations and infections due to Chlamydiae and Mycoplasms. An these microbial agents probably interfere with complex immunological pathways, thus contributing to induce and exacerbate asthma in genetically predisposed individuals. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：775 / 784

页数：10

共 76 条

[1] Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma [J].