Diastereo- and enantioselective synthesis of α,β-disubstituted γ-nitro methyl sulfonates

被引：30

作者：

Enders, D

Berner, OM

Vignola, N

Bats, JW

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

[2] Univ Frankfurt, Inst Organ Chem, D-60439 Frankfurt, Germany

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 23期

关键词：

D O I：

10.1039/b108567k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel asymmetric synthesis of highly enantioenriched homotaurine precursors has been developed via diastereoselective Michael addition of lithiated enantiopure sulfonates to nitroalkenes by using 1,2:5,6-di-O-isopropylidene-alpha -D-allofuranose as chiral auxiliary.

引用

页码：2498 / 2499

页数：2

共 18 条

[1] Enders D, 2000, ANGEW CHEM INT EDIT, V39, P4605, DOI 10.1002/1521-3773(20001215)39:24<4605::AID-ANIE4605>3.0.CO
[2] 2-X
[3] Enders D, 1999, SYNLETT, P747
[4] Enders D, 2000, SYNLETT, P637
[5] ENDERS D, 2000, ANGEW CHEM, V112, P4774
[6] ENDERS D, 2001, IN PRESS ANGEW CHEM
[7] FERINGA BL, 1995, STEREOSELECTIVE SY B, V21, P2104
[8] KALIR A, 1991, CHEM SULFONIC ACIDS, P767
[9] Krogsgaard-Larsen P., 1990, COMPREHENSIVE MED CH, V3, P493
[10] Leonard J, 1998, EUR J ORG CHEM, V1998, P2051

← 1 2 →