Intramolecular cyclopropanation of unsaturated terminal aziridines

被引：25

作者：

Hodgson, DM ^{[1
]}

Humphreys, PG ^{[1
]}

Ward, JG ^{[1
]}

机构：

[1] Univ Oxford, Chem Res Lab, Dept Chem, Oxford OX1 3TA, England

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 05期

关键词：

D O I：

10.1021/ol060101n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regio- and stereoselective deprotonation of bishomoallylic terminal N-Bus (Bus = tert-butylsulfonyl)-protected aziridines generate aziridinyl anions that undergo diastereoselective intramolecular cyclopropanation giving trans-2-aminobicyclo[3.1.0]hexanes in good to excellent yields.

引用

页码：995 / 998

页数：4

共 41 条

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