Detection of novel divergent arenaviruses in bold snakes with inclusion body disease in The Netherlands

被引：58

作者：

Bodewes, R. ^{[1
]}

Kik, M. J. L. ^{[2
]}

Raj, V. Stalin ^{[1
]}

Schapendonk, C. M. E. ^{[1
]}

Haagmans, B. L. ^{[1
]}

Smits, S. L. ^{[1
,3
]}

Osterhaus, A. D. M. E. ^{[1
,3
]}

机构：

[1] Erasmus MC, Dept Virosci, Rotterdam, Netherlands

[2] Univ Utrecht, Dept Pathobiol, Fac Vet Med, Utrecht, Netherlands

[3] Viroclin Biosci BV, Rotterdam, Netherlands

来源：

JOURNAL OF GENERAL VIROLOGY | 2013年 / 94卷

关键词：

D O I：

10.1099/vir.0.051995-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Arenaviruses are bi-segmented negative-stranded RNA viruses, which were until recently only detected in rodents and humans. Now highly divergent arenaviruses have been identified in boid snakes with inclusion body disease (IBD). Here, we describe the identification of a new species and variants of the highly divergent arenaviruses, which were detected in tissues of captive boid snakes with IBD in The Netherlands by next-generation sequencing. Phylogenetic analysis of the complete sequence of the open reading frames of the four predicted proteins of one of the detected viruses revealed that this virus was most closely related to the recently identified Golden Gate virus, while considerable sequence differences were observed between the highly divergent arenaviruses detected in this study. These findings add to the recent identification of the highly divergent arenaviruses in boid snakes with IBD in the United States and indicate that these viruses also circulate among boid snakes in Europe.

引用

页码：1206 / 1210

页数：5

共 17 条

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