An enantio- and diastereo-controlled synthesis of (-)-neplanocin A and its 2,3-di-epi isomer

被引：44

作者：

Trost, BM

Madsen, R

Guile, SD

机构：

[1] Department of Chemistry, Stanford University, Stanford

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 10期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(97)00176-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective Pd catalyzed desymmetrization of cis-3,5-dibenzoyloxycyclopent-2-ene combined with a diastereoselective epoxidation provided a common intermediate that can bifurcate to form either (-)-neplanocin A or its 2,3-di-epi isomer. (C) 1997 Elsevier Science Ltd.

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页码：1707 / 1710

页数：4

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