Synthesis, characterisation and mass spectrometric fragmentation of O-(chlorodifluoroacylated) alcohols

被引：6

作者：

Bhadury, PS ^{[1
]}

Palit, M ^{[1
]}

Sharma, M ^{[1
]}

Raza, SK ^{[1
]}

Jaiswal, DK ^{[1
]}

机构：

[1] Def Res & Dev Estab, Gwalior 474002, India

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2002年 / 113卷 / 01期

关键词：

sodium chlorodifluoroacetate; polyfluorinated alcohols; esterification; mass spectrometric fragmentation; tandem mass spectrometry; F-19; NMR;

D O I：

10.1016/S0022-1139(01)00465-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An indirect and uncatalysed esterification of chlorodifluoroacetic acid with polyfluoro and hydrocarbon alcohols has been developed. The method which involves the reaction between sodium chlorodifluoroacetate and alcohols in dimethylformamide (DMF) is particularly facile with polyfluorinated alcohols resulting in esters in 71-85% yield. The esters have been characterised on the basis of H-1 and F-19 NMR and mass spectral data. The electron impact (EI) mass spectrometric fragmentation of these polyfluorinated esters have shown some interesting features which have been substantiated by using tandem mass spectrometry. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：47 / 50

页数：4

共 7 条

[1] Synthesis of 2-phenylperfluoropropene and 1,1,1,3,3,3-hexafluoro-2-phenylpropane [J].