New α-tetralonyl glucosides from the fruit of Juglans mandshurica

被引:96
作者
Liu, L
Li, W
Koike, K
Zhang, S
Nikaido, T
机构
[1] Toho Univ, Fac Pharmaceut Sci, Chiba 2748510, Japan
[2] Heilongjiang Provincial Inst Drug Control, Dept Chinese Trad Med, Harbin 150001, Peoples R China
关键词
Juglans mandshurica; Juglandaceae; alpha-tetralonyl glucoside; juglanoside;
D O I
10.1248/cpb.52.566
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
Five new alpha-tetralonyl glucosides, juglanosides A-E (1-5) were isolated from the fresh rejuvenated fruit of Juglans mandshurica. Their structures were elucidated as (4S)-4-hydroxy-alpha-tetralone 4-O-beta-D-glucopyranoside (1), (4S)-4,5-dihydroxy-alpha-tetralone 4-O-beta-D-glueopyranoside (2), (4S)-4,6-dihydroxy-alpha-tetralone 4-O-beta-D-glucopyranoside (3), (4S)-4,5,8-trihydroxy-alpha-tetralone 4-O-beta-D-glucopyranoside (4), and (4S)-4,5,8-trihydroxy-alpha- tetralone 5-O-beta-D-glueopyranoside (5) on the basis of spectroscopic analysis and chemical evidence.
引用
收藏
页码:566 / 569
页数:4
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