Phototriggering of liposomal drug delivery systems

被引:194
作者
Shum, P
Kim, JM
Thompson, DH [1 ]
机构
[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
[2] Janus Biosyst Inc, W Lafayette, IN 47906 USA
关键词
light-sensitive liposomes; photopolymerization; photooxidation; plasmenylcholines; photodeprotection; photoacid generation;
D O I
10.1016/S0169-409X(01)00232-0
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Over the past several years, photodynamic therapy (PDT) has been approved for the treatment of various cancers. Additional applications of photochemical processes for triggering site-specific drug delivery are in early stages of development at this time. This review focuses on the literature appearing between January 1996-June 2001 that describe new and ongoing studies of phototriggering mechanisms that may ultimately find utility in drug delivery applications. (C) 2001 Published by Elsevier Science B.V.
引用
收藏
页码:273 / 284
页数:12
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