LC(50) of 2-bromopropane

被引：8

作者：

Kim, HY ^{[1
]}

Chung, YH ^{[1
]}

Yi, KH ^{[1
]}

Kim, JG ^{[1
]}

Yu, IJ ^{[1
]}

机构：

[1] KOREA IND SAFETY CORP,IND HLTH RES INST,DEPT IND TOXICOL,BUPYUNG GU,INCHON 403120,SOUTH KOREA

来源：

INDUSTRIAL HEALTH | 1996年 / 34卷 / 04期

关键词：

2-bromopropane; isopropyl bromide; acute inhalation toxicity; LC(50); mouse; Solvent; 5200;

D O I：

10.2486/indhealth.34.403

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

LC(50) of 2-bromopropane was reexamined by using the OECD guideline in ICR mouse. The mice, 3 males and 3 females, were exposed to 2-bromopropane at five different concentrations for 4 h in inhalation chambers. The exposed animals were observed for 14 days. The animals which had survived and died were counted for the LC(50) determination. The LC(50) was calculated by using a dose-mortality curve at a 95 percent confidence level, The LC(50) was 31,171 ppm, and the lowest lethal concentration (LLC) was lower than 29,528 ppm and the lethal concentration at 100% (LC(100)) was higher than 32,905 ppm.

引用

页码：403 / 407

页数：5