Adherence to HAART among patients with HIV: breakthroughs and barriers

被引:104
作者
Ickovics, JR [1 ]
Meade, CS [1 ]
机构
[1] Yale Univ, Sch Med, Dept Epidemiol & Publ Hlth, New Haven, CT 06520 USA
来源
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2002年 / 14卷 / 03期
关键词
D O I
10.1080/09540120220123685
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Highly active antiretroviral therapy (HAART) has been a major breakthrough for the treatment of patients with HIV; however, adherence to treatment remains a formidable barrier. This paper evaluates the current state-of-the-science in adherence to HAART. Barriers to treatment success, determinants of adherence and interventions to improve adherence are reviewed. Overall, multifaceted interventions appear most promising. We conclude with recommendations to enhance clinical practice and improve treatment outcomes for patients with HIV. Despite substantial attention to adherence in recent years, much more remains to be done to understand and promote adherence to HAART.
引用
收藏
页码:309 / 318
页数:10
相关论文
共 70 条
[1]  
Altice FL, 2001, J ACQ IMMUN DEF SYND, V28, P47, DOI 10.1097/00042560-200109010-00008
[2]  
ANDRADE A, 2001, 8 C RETR OPP INF CHI
[3]  
[Anonymous], 2001, AIDS and Behavior
[4]  
[Anonymous], 8 C RETR OPP INF CHI
[5]   Helping the urban poor stay with antiretroviral HIV drug therapy [J].
Bamberger, JD ;
Unick, J ;
Klein, P ;
Fraser, M ;
Chesney, M ;
Katz, MH .
AMERICAN JOURNAL OF PUBLIC HEALTH, 2000, 90 (05) :699-701
[6]   Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population [J].
Bangsberg, DR ;
Hecht, FM ;
Charlebois, ED ;
Zolopa, AR ;
Holodniy, M ;
Sheiner, L ;
Bamberger, JD ;
Chesney, MA ;
Moss, A .
AIDS, 2000, 14 (04) :357-366
[7]   Non-adherence to highly active antiretroviral therapy predicts progression to AIDS [J].
Bangsberg, DR ;
Perry, S ;
Charlebois, ED ;
Clark, RA ;
Roberston, M ;
Zolopa, AR ;
Moss, A .
AIDS, 2001, 15 (09) :1181-1183
[8]  
BARTLETT J, 2000, 13 INT AIDS C DURB
[9]  
BENTZ L, 2001, 5 INT C BIOPS ASP HI
[10]   Management of the adverse effects of antiretroviral therapy and medication adherence [J].
Blake, M ;
Sherer, R .
CLINICAL INFECTIOUS DISEASES, 2000, 30 :S96-S116