Tissue factor initiated blood coagulation

被引：35

作者：

Gomez, K ^{[1
]}

McVey, JH ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, MRC, Ctr Clin Sci, London W12 0NN, England

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2006年 / 11卷

基金：

英国医学研究理事会;

关键词：

blood; coagulation; tissue factor; factor VII; review;

D O I：

10.2741/1888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tissue factor (TF) is the cellular receptor and cofactor for blood coagulation factor (F) VII. Exposure of flowing blood to cells that express TF leads to the initiation of blood coagulation. Blood coagulation is tightly regulated to generate a local fibrin clot at the site of vascular injury without compromising blood flow in the vasculature. This chapter describes the initiation and propagation of the response and how it is ultimately down-regulated to prevent widespread inappropriate blood coagulation.

引用

页码：1349 / 1359

页数：11

共 59 条

[1] Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain [J].

Ahamed, J ;

Ruf, W .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (22) :23038-23044

[2] A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome [J].

Albrecht, C ;

McVey, JH ;

Elliott, JI ;

Sardini, A ;

Kasza, I ;

Mumford, AD ;

Naoumova, RP ;

Tuddenham, EGD ;

Szabo, K ;

Higgins, CF .

BLOOD, 2005, 106 (02) :542-549

[3] The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor [J].

Banner, DW ;

DArcy, A ;

Chene, C ;

Winkler, FK ;

Guha, A ;

Konigsberg, WH ;

Nemerson, Y ;

Kirchhofer, D .

NATURE, 1996, 380 (6569) :41-46

[4] Regulation of angiogenesis by tissue factor cytoplasmic domain signaling [J].

Belting, M ;

Dorrell, MI ;

Sandgren, S ;

Aguilar, E ;

Ahamed, J ;

Dorfleutner, A ;

Carmeliet, P ;

Mueller, BM ;

Friedlander, M ;

Ruf, W .

NATURE MEDICINE, 2004, 10 (05) :502-509

[5] Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis [J].

Bozzini, C ;

Girelli, D ;

Bernardi, F ;

Ferraresi, P ;

Olivieri, O ;

Pinotti, M ;

Martinelli, N ;

Manzato, F ;

Friso, S ;

Villa, G ;

Pizzolo, F ;

Beltrame, F ;

Corrocher, R .

THROMBOSIS AND HAEMOSTASIS, 2004, 92 (03) :541-549

[6] Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation [J].

Bugge, TH ;

Xiao, Q ;

Kombrinck, KW ;

Flick, MJ ;

Holmback, K ;

Danton, HJS ;

Colbert, MC ;

Witte, DP ;

Fujikawa, K ;

Davie, EW ;

Degen, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (13) :6258-6263

[7] A new role in hemostasis for the adhesion receptor P-selectin [J].

Cambien, B ;

Wagner, DD .

TRENDS IN MOLECULAR MEDICINE, 2004, 10 (04) :179-186

[8] Role of tissue factor in embryonic blood vessel development [J].

Carmeliet, P ;

Mackman, N ;

Moons, L ;

Luther, T ;

Gressens, P ;

VanVlaenderen, I ;

Demunck, H ;

Kasper, M ;

Breier, G ;

Evrard, P ;

Muller, M ;

Risau, W ;

Edgington, T ;

Collen, D .

NATURE, 1996, 383 (6595) :73-75

[9]

Chang JY, 1999, THROMB HAEMOSTASIS, V81, P45

[10] In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease [J].

Contrino, J ;

Hair, G ;

Kreutzer, DL ;

Rickles, FR .

NATURE MEDICINE, 1996, 2 (02) :209-215

← 1 2 3 4 5 6 →