Impact of COVID-19 pandemic on rheumatoid arthritis from a Multi-Centre patient-reported questionnaire survey: influence of gender, rural-urban gap and north-south gradient

被引:40
作者
Abualfadl, Esam [1 ]
Ismail, Faten [2 ]
El Shereef, Rawhya R. [2 ]
Hassan, Eman [3 ]
Tharwat, Samar [4 ]
Mohamed, Eman F. [5 ]
Abda, Essam A. [6 ]
Radwan, Ahmed R. [1 ]
Fawzy, Rasha M. [7 ]
Moshrif, Abdel Hafeez [8 ]
Noor, Rasha Abdel [9 ]
Senara, Soha [10 ]
Abd Elazim, Mervat I. [11 ]
Abaza, Nouran M. [12 ]
Raafat, Hala A. [13 ]
El-Gazzar, Iman I. [13 ]
El-Hammady, Dina H. [14 ]
Hammam, Nevin [6 ,15 ]
Gheita, Tamer A. [13 ]
El-Mallah, Reem [12 ]
机构
[1] Sohag Univ, Rheumatol Dept, Fac Med, Sohag, Egypt
[2] Minia Univ, Rheumatol Dept, Fac Med, Al Minya, Egypt
[3] Alexandria Univ, Fac Med, Rheumatol Unit, Internal Med Dept, Alexandria, Egypt
[4] Mansoura Univ, Fac Med, Rheumatol Unit, Internal Med Dept, Dakahlia, Egypt
[5] Al Azhar Univ, Fac Med Girls, Rheumatol Unit, Internal Med Dept, Cairo, Egypt
[6] Assiut Univ, Rheumatol Dept, Fac Med, Assiut, Egypt
[7] Benha Univ, Rheumatol Dept, Fac Med, Kalyoubia, Egypt
[8] Al Azhar Univ, Rheumatol Dept, Fac Med, Assiut, Egypt
[9] Tanta Univ, Internal Med Dept, Rheumatol Unit, Fac Med, Tanta, Egypt
[10] Fayoum Univ, Rheumatol Dept, Fac Med, Al Fayyum, Egypt
[11] Beni Suef Univ, Rheumatol Dept, Fac Med, Bani Suwayf, Egypt
[12] Ain Shams Univ, Rheumatol Dept, Fac Med, Cairo, Egypt
[13] Cairo Univ, Rheumatol Dept, Fac Med, Cairo, Egypt
[14] Helwan Univ, Rheumatol Dept, Fac Med, Cairo, Egypt
[15] Univ San Francisco, Rheumatol Dept, San Francisco, CA USA
关键词
Coronavirus Disease 2019 (COVID-19); Rheumatoid arthritis; Multi-centre; Patient-reported questionnaire; Infection; North-south gradient;
D O I
10.1007/s00296-020-04736-9
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
During the coronavirus disease-2019 (COVID-19) pandemic there were several barriers to treatment access and medication adherence in rheumatoid arthritis (RA) patients. There is no information regarding the RA patient health status in Egypt during the COVID-19. Thus,the aim of this work was to study the impact of the pandemic on RA patients through a patient-reported questionnaire and to determine the influence of gender, geographic regions. This multi-centre study initiated by the Egyptian College of Rheumatology (ECR) was conducted on 1037 RA patients attending rheumatology clinics from 10 governorates. The questionnaire provided covered socio-demographic data, health/disease status, information/knowledge about COVID-19 and medical/family history of the infection. Patients mean age was 44.2 +/- 12.3 years;855 females and 182 males; 539(52%) from rural and 497(48%) from urban areas. 41.8% reported a striking difficulty to obtain hydroxychloroquine during the pandemic. The majority (70%) considered maintaining a regular visit to the rheumatologist in addition to remote contact mainly by phone (44.4%) or via WhatsApp (33.1%), in particular among male and urban patients. Urban patients were more likely to be infected by COVID-19 (12.9% vs 6.2%; p 0.0001) than rural. Northern cities had more patients with suspected COVID-19 (13.9% vs 6.1%; p 0.0001); was significantly associated with more disease flares (30.8% vs 5.8%) with subsequent change in the RA treatment (20.9% vs 6.4%; p 0.0001). Patients with RA faced remarkable difficulty to obtain their medications with subsequent change in their disease status. The challenges of the pandemic have hastened changes in the way we deliver health care.
引用
收藏
页码:345 / 353
页数:9
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