Bone Healing: The Diamond Concept

被引:10
作者
Giannoudis, Peter V. [1 ,2 ,3 ]
Panteli, Michalis [3 ]
Calori, Giorgio Maria [4 ]
机构
[1] Leeds Gen Infirmary, Acad Dept Trauma & Orthopaed, Clarendon Wing,Level A,Great George St, Leeds LS1 3EX, W Yorkshire, England
[2] Univ Leeds, LIMM Sect Musculoskeletal Dis, Leeds, W Yorkshire, England
[3] Univ Leeds, Sch Med, Acad Dept Trauma & Orthopaed Surg, Leeds LS2 9JT, W Yorkshire, England
[4] Univ Milan, Sch Med, Acad Dept Trauma & Orthopaed Surg, Milan, Italy
来源
EUROPEAN INSTRUCTIONAL LECTURES, VOL 14 | 2014年 / 14卷
关键词
MESENCHYMAL STEM-CELLS; ENDOTHELIAL PROGENITOR CELLS; OPEN TIBIAL FRACTURES; MORPHOGENETIC PROTEINS; NON-UNIONS; MULTICENTER EXPERIENCE; GENETIC PREDISPOSITION; MOLECULAR ASPECTS; ILIAC CREST; REPAIR;
D O I
10.1007/978-3-642-54030-1_1
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
100224 [整形外科学];
摘要
The incidence of fracture non-union has been estimated to be as high as 10 %. The treatment of fracture non-union remains challenging even for the most experienced surgeons. The presence of a poor soft tissue envelope, deformity, avascular bone edges, reduced bone stock, low-grade infection and patient related co-morbidities are some of the important contributing factors that need to be addressed. Evaluation of the complexity of the non-union and formulating the appropriate pre-operative plan and treatment modality requires good understanding of the pathogenicity of this condition and having extensive surgical experience. The state of both the mechanical and biological environment, is thought to play a crucial role in the decision making process regarding revision surgery. Application of the so-called 'diamond concept' provides the optimum mechano-biological conditions for bone repair and should be considered in cases where difficulties to achieve union are anticipated.
引用
收藏
页码:3 / 16
页数:14
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