Short retroposons in eukaryotic genomes

被引：172

作者：

Kramerov, DA ^{[1
]}

Vassetzky, NS ^{[1
]}

机构：

[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 119991, Russia

来源：

INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 247 | 2005年 / 247卷

基金：

俄罗斯基础研究基金会;

关键词：

repetitive elements; mobile elements; transposons; transposable elements; retroposons; SINEs; RNA polymerase III;

D O I：

10.1016/S0074-7696(05)47004-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Short retroposons (SINEs) are repetitive elements amplified in the genome via an RNA intermediate, using the enzymatic machinery of autonomous retroposons (LINEs). SINEs are widely distributed in eukaryotes; for instance, all tested mammalian genomes contain 10(4)-10(6) SINE copies. Although several SINE families such as primate Alu or rodent B1 have long been recognized, the more recent discovery of many SINEs in various eukaryotes, as well as progress in understanding the mechanisms of LINE replication and genome functioning as a whole, shed light on the biology and evolution of SINEs and their significance for the cell.

引用

页码：165 / +

页数：63

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