Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma

被引:122
作者
Ciarapica, Roberta [3 ]
Russo, Guiseppe [3 ,4 ,7 ]
Verginelli, Federica
Raimondi, Lavinia
Donfrancesco, Alberto [2 ]
Rota, Rosella [1 ]
Giordano, Antonio [3 ,5 ,6 ]
机构
[1] OPBG, Lab Angiogenesis, Res Inst, I-00165 Rome, Italy
[2] OPBG, Dept Clin Oncol, I-00165 Rome, Italy
[3] Temple Univ, Coll Sci & Technol, Ctr Biotechnol, Sbarro Inst Canc Res & Mol Med, Philadelphia, PA 19122 USA
[4] Univ Genoa, DISI Dept Comp & Informat Sci, Genoa, Italy
[5] Univ Siena, Dept Human Pathol & Oncol, I-53100 Siena, Italy
[6] CROM, Avellino, Italy
[7] Human Hlth Fdn Onlus, Spoleto, Italy
关键词
rhabdomyosarcoma; miRNAs; miR-26a; Ezh2; muscle differentiation; MICRORNA EXPRESSION; MIR-17-92; CLUSTER; UP-REGULATION; SKELETAL; TARGETS; GROWTH; MYOGENIN; CANCER;
D O I
10.4161/cc.8.1.7292
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:172 / 175
页数:4
相关论文
共 23 条
[1]   Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR [J].
Begum, S ;
Emani, N ;
Cheung, A ;
Wilkins, O ;
Der, S ;
Hamel, PA .
ONCOGENE, 2005, 24 (11) :1860-1872
[2]   MicroRNAs in skeletal and cardiac muscle development [J].
Callis, Thomas E. ;
Chen, Jian-Fu ;
Wan, Da-Zhi .
DNA AND CELL BIOLOGY, 2007, 26 (04) :219-225
[3]   The Polycomb EA2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation [J].
Caretti, G ;
Di Padova, M ;
Micales, B ;
Lyons, GE ;
Sartorelli, V .
GENES & DEVELOPMENT, 2004, 18 (21) :2627-2638
[4]   Nasopharyngeal carcinoma: molecular biomarker discovery and progress [J].
Cho, William Chi-shing .
MOLECULAR CANCER, 2007, 6 (1)
[5]   Upregulation of miR-23a∼27a∼24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells [J].
Huang, Shenglin ;
He, Xianghuo ;
Ding, Jie ;
Liang, Linhui ;
Zhao, Yingjun ;
Zhang, Zhenfeng ;
Yao, Xiao ;
Pan, Zhimei ;
Zhang, Pingping ;
Li, Jinjun ;
Wan, Dafang ;
Gu, Jianren .
INTERNATIONAL JOURNAL OF CANCER, 2008, 123 (04) :972-978
[6]   Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival [J].
Jiang, Jinmai ;
Gusev, Yuriy ;
Aderca, Ileana ;
Mettler, Teresa A. ;
Nagorney, David M. ;
Brackett, Daniel J. ;
Roberts, Lewis R. ;
Schmittgen, Thomas D. .
CLINICAL CANCER RESEARCH, 2008, 14 (02) :419-427
[7]   MicroRNA expression profiles classify human cancers [J].
Lu, J ;
Getz, G ;
Miska, EA ;
Alvarez-Saavedra, E ;
Lamb, J ;
Peck, D ;
Sweet-Cordero, A ;
Ebet, BL ;
Mak, RH ;
Ferrando, AA ;
Downing, JR ;
Jacks, T ;
Horvitz, HR ;
Golub, TR .
NATURE, 2005, 435 (7043) :834-838
[8]   miRiad roles for the miR-17-92 cluster in development and disease [J].
Mendell, Joshua T. .
CELL, 2008, 133 (02) :217-222
[9]   Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines [J].
Meng, Fanyin ;
Henson, Roger ;
Lang, Molly ;
Wehbe, Hania ;
Maheshwari, Shail ;
Mendell, Joshua T. ;
Jiang, Jinmai ;
Schmittgen, Thomas D. ;
Patel, Tushar .
GASTROENTEROLOGY, 2006, 130 (07) :2113-2129
[10]   The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells [J].
Mertens-Talcott, Susanne U. ;
Chintharlapalli, Sudhakar ;
Li, Mangrong ;
Safe, Stephen .
CANCER RESEARCH, 2007, 67 (22) :11001-11011