Direct catalytic intermolecular α-allylic alkylation of aldehydes by combination of transition-metal and organocatalysis

被引：335

作者：

Ibrahem, I ^{[1
]}

Córdova, A ^{[1
]}

机构：

[1] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 12期

关键词：

aldehydes; allylation; homogeneous catalysis; organocatalysis;

D O I：

10.1002/anie.200504021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) All in the same pot together: The direct catalytic α-allylic alkylation of aldehydes and cyclic ketones is achieved by using a simple, unprecedented one-pot procedure. Transition-metal and enamine catalysis are combined so that α-allylic alkylated aldehydes and cyclic ketones are formed in high yield with a direct catalytic chemo- and regioselective method. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1952 / 1956

页数：5

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